吴勇杰
吴勇杰,研究所所长/甘肃省新药临床前研究重点实验室副主任。
一、科研方向
抗肿瘤药理学。
新药药理学。
抗炎与免疫药理学。
Research Interests:
Antitumor Pharmacology。
Preclinical Pharmacology of New Drugs。
Anti-inflammatory Pharmacology。
二、荣誉称号及奖励
1992年获甘肃省青年教师成材奖。
《葡萄籽原花青素经肠给药系统的临床前研究》,2006年获甘肃省科技进步2等奖,1/5。
《葡萄籽中原花青素对阿霉素增效减毒作用及机理研究》获2006年获甘肃省自然科学奖,(3/5)。
《组织修复及炎症过程中不同蛋白类药物的药理、毒理作用及其机理的实验研究》, 2008年获甘肃省科技进步2等奖,5/5。
1998年12月入选“333科技人才工程、甘肃省跨世纪学术技术带头人。2006年获国务院政府特殊津贴。
honors and awards:
1992 obtained the honor of TheYoung Teachers Chengcai Award in Gansu Province 。
1998 obtained the honor of Academic technology leaders of Gansu Province。
2006 obtaine the second prize of Gansu Provincial Science and Technology Progress Award (First author) for Sdudy on Enteral delivery systems of Proanthocyanidin from Grape Seeds。
2006 obtained the second prize of Gansu Provincial Natural Science (Third author) for the Mechanisms of Proanthocyanidin from Grape Seeds in both Potentiating Anti-tumor Activity and Reducing Toxicity of Doxorubicin。
2006 obtained the honor of special allowance of Government of the State Council。
三、个人简历
教育背景:
1976.09至1979.09: 兰州医学院临床医学专业读大学。
1982.01至1984.12:在山西医学院药理学专业读硕士研究生。
1988.03至1989.03:公派出国在日本国岐阜大学医学部药理学教研室进修药理学一年
工作经历:
1985.04至2004.11: 在兰州医学院药理学专业任教。
2004.11至2007.12:在9193澳门永利场药学院药理学专业任教。
2007.12至2009.03:在9193澳门永利场基础医学院药理学专业任教。
2006.10至2009.03任甘肃省新药临床前研究重点实验室副主任。
Resume:
Education:
Sept. 1996至June 1999 Students. in Clinical Medicine Department of Lanzhou Medical College of China。
Jan. 2002至Dec 2004 Master Degree in Pharmacology, the Department of Pharmacology of Shanxi Medical College, China。
Mar. 1988至Mar 1989 Visiting Scholar in Department of Pharmacology of Gifu University,Japan。
Working Experiences
Jul. 1997至-Now Professor, Institute of Pharmacology,School of Basic Medicine Science, Lanzhou University, China 。
Apr. 1985至Jun. 1997 A teaching assistant, then Lecturer in Department of Pharmacology,Lanzhou Medical College,.China。
四、发表论文
LI Xiao-li, Cai Yong-qing Qin Hong WU Yong-jie (corresponding Author),The therapeutic effect and mechanism of proanthocyanidins from grape seeds in rats with TNBS-induced ulcerative colitis. Can J Physiol Pharmacol.2008;86:841-849。
崔明霞,高?,闵光宁,王莉,路莉,张宝来,吴勇杰*(通讯作者),.造模持续时间对大鼠高营养性肥胖模型制备的影响 中国药理学通报. 2008;24(3):412-6。
李志成,覃红,吴勇杰*(通讯作者),.大鼠肌注伤寒Vi多糖蛋白结合疫苗的长期毒性. 中国新药杂志. 2008;17(7):565。
孙炯,吴勇杰*(通讯作者),李文广,高明堂.应用?窝淋巴结实验评价干扰素的免疫毒性 中国药理学通报 2005; 21(8):974-77。
鞠洋,路莉,吴勇杰*(通讯作者),高明堂,李文广,闵光宁.ELISA法研究新型重组人肿瘤坏死因子在小鼠体内的药代动力学. 中国药理学通报 2005; 21(7):847-51。
Xiaoyu ZHANG, Decheng BAI, Yongjie WU, Wenguang LI and Naifa LIU. Proanthocyanidin from grape seeds enhances anti-tumor effect of doxorubicin both in vitro and in vivo. Pharmazie. 2005; 60(7): 533?538。
10.路莉,吴勇杰*(通讯作者),,高明堂,李文广. 重组人碱性成纤维细胞生长因子胶囊对大鼠慢性胃溃疡愈合质量的影响. 中国药理学通报 2004;20:75-8。
Chang Lin, Zhang Zhao, Wu Yong-Jie (corresponding Author), Zhu Ren-Zhi.Effects of recombinant human basic fibroblast growth factor on restenosis after arterial endothelial injury in rats. Acta Pharmacol Sin 2001; 22(10): 876-80。
ZHANG Yi, WANG Jun-zhi, WU Yong-jie and LI Wen-guang. Anti-inflammatory effect of recombinant human superoxide dismutase in rats and mice and its mechanism. Acta Pharmacologica Sinica. 2002; 23(5):439-444。
WANG Jun-zhi, WU Yong-jie, RAO Chun-ming, GAO Ming-tang and LI Wen-guang. Effect of recombinant human basic fibroblast growth factor on stomach ulcers in rats and mice. Acta Pharmacologica Sinica. 1999; 20(8):763-768。
WU Yong-jie, LI Wen-guang, ZHANG Zhen-ming and TIAN Xuan. Antioxidative activity of 4-oxy and 4-hydroxy nitroxides in tissues and erythrocytes from rats. Acta Pharmacologica Sinica. 1997; 18(6):510-514。
WANG Jun-zhi, BAI De-cheng, RAO Chun-ming, LI Wen-guang, GAO Ming-tang, WANG Xiao-qi and WU Yong-jie. Effects of 2.5s mouse nerve growth factor on regeneration of injured sciatic nerves in mice and rats. Acta Pharmacologica Sinica. 1997; 18(6):501-504。
Wu Yong-Jie,Li Xin-Fang. Effects of sodium 18 beta-glycrrhetinic acid on the production of active oxygen species and the concentration of intracellular free Ca2+ in rat neutrophils. Acta Pharmacol Sin 1991;12(2):280-4。
Wu Yong-Jie,Zhou Er-feng.Effect of methylflavonolamine on platelet aggregation in rabbits. Acta Pharmacol Sin 1988,9(1):79-83。